Wesley Crusher – Wil Wheaton
We might lose a Trekkies by including Wil Wheaton on this list, as his character was met with tons of opposition, but alas we must. Wesley Crusher appeared in the first four seasons of Star Trek: The Next Generation which then quickly turned into a recurring role. Since then, he starred in some independent films and television shows such as Criminal Minds and The Big Bang Theory.
William T. Riker – Jonathan Frakes
Get this: Jonathan Frakes is one of two Star Trek regulars to appear on four different series, including Star Trek: The Next Generation, Star Trek: Deep Space Nine, Star Trek: Voyager, and Star Trek: Enterprise. Furthermore Frakes directed episodes of the show and also others that aren’t related to Star Trek. Lest we forget, he’s also a published author.